Presentation and negotiation of the documents

Dear Freinds,

please help to answer the following questions:

1. Could Beneficiary present documents to the bank other than stated in field 41A if concrete bank stated there.

Could issuing bank refuse to honour/negotiate documents if docs presented directly to the issuing bank omitting advising bank? omitting nominating bank ?

2. Could Beneficiary present documents directly to the issuing bank omitting confirming bank (LC is already confirmed). Could issuing bank refuse to honour/negotiate documents in this case ?

 

Thank you in advance for your precious assistance!